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Key Information:

  • The Difference: Have you heard of the “mini-pill” and wondered how it differs from the combined contraceptive pill? The key difference is that the progesterone-only pill (POP) contains no oestrogen.
  • How it Works: The most commonly prescribed type (desogestrel) works by stopping your ovaries from releasing an egg each month.
  • Effectiveness: When taken correctly, it is over 99% effective at preventing pregnancy.
  • Who is it for?: Because it is oestrogen-free, it is a popular choice for those who cannot, or prefer not to, use contraception containing oestrogen (eg those who are breastfeeding). It can also help manage painful or heavy periods and endometriosis symptoms.

Is it Safe for Me?

While very safe for many, a health check is still necessary before starting. A clinician needs to check for:

  • History of breast cancer.
  • Severe liver conditions.
  • Specific heart, blood vessel, or kidney issues.

Where Can I Get It?

Accessing the mini-pill is flexible and confidential.

  • The Practice or Clinics: Available free from us or sexual health clinics.
  • Pharmacies (Free Consultation): Many pharmacists can now supply the mini-pill free of charge after a private consultation (saving you a GP appointment).
  • Pharmacies (Over the Counter): You can also buy certain brands of the mini-pill directly over the counter without a prescription.

What Happens Next?

If you need an oestrogen-free option, you can visit your local pharmacy or contact us to discuss if the mini-pill is right for you.

Discuss Your Contraception
 

Further Information

For more information on the progesterone-only pill, where to get it, who can take it, side effects, risks and more, please visit the NHS website.

Learn more about the progesterone-only pill

Last reviewed: 27 December 2025
Next review due: 27 December 2028